Infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy following twelve months or more of regular unprotected sexual intercourse. Randomised trials evaluating treatments for subfertility have reported many different outcomes and outcome measures. Such variation contributes to an inability to compare and combine individual trials, limiting the usefulness of evidence synthesis to inform clinical practice.
COMMIT-MaleInferility seeks to develop a core outcome set for male infertility trials and form part of the wider COMMIT project.
James M N Duffy
- COS for clinical trials or clinical research
- Consensus meeting
- Delphi process
- Literature review