Stroke is one of the leading causes of morbidity and mortality in both developed and developing countries, and has been the top leading cause of death in China. Traditional Chinese medicine (TCM) has a unique therapeutic effect in the treatment of cerebral infarction. However, the standardization of clinical trials limits the development of TCM on treatment of cerebral infarction, such as no accepted outcomes or indices applied for assessments, or no consensus among the varied outcomes or indices, or high risks of the selective reported bias or lots of missing data, etc. It is necessary to establish a Core Outcome Set for for cerebral infarction in clinical trials of TCM.Contributors
Yunling Zhang is the principal investigator.
Xiyuan Hospital of CACMS, Beijing, China
- COS for clinical trials or clinical research
- COS for practice
- Consensus meeting
- Delphi process
- Systematic review
Conduct a systematic review and interview to develop an outcome list. And then we will conduct two or three rounds of Delphi process and a consensus meeting to develop a core outcome set.