Developing a Core outcome set of Traditional Chinese Medicine on Lung Cancer

Lung cancer is one of the most common malignant tumors, with the incidence rate ranked top two among all other tumors, and on the rise annually. Surgical treatment has been deemed to be a reliable mean in curing and obtaining long term efficacy in early stage lung cancer, but the results are not satisfactory. The recurrence and metastasis rate of lung cancer are high. Radiotherapy and chemotherapy, though effective for some patients, have strong side effects and most of them only have palliative effect. Traditional Chinese medicine for lung cancer can be used in improving therapeutic efficacy, reducing toxicity, improving immunity of the body ,as well as improving quality of life and prolonging survival time. Relevant clinical trials increase year by year. However, the heterogeneous reporting of outcomes in these trials has hindered synthesizing clinical results in meta-analyses, which reduce the value of clinical trials. Meanwhile, it may exist risk of selective outcome reporting bias in clinical trials. Hence, developing core outcome set(COS)for clinical trials in the field of Traditional Chinese Medicine(TCM)is necessary and urgent. This research aims to establish COS for clinical trials of lung cancer in TCM.

Contributors

Principal investigator:
Junhua Zhang,Mingyan Zhang,Evidence-Based Medicine Center,Tianjin University of Traditional Chinese Medicine,Tianjin,China
Other contributors: Hui ZI CHUA,Kai Li,Bohan Niu,Evidence-Based Medicine Center,Tianjin University of Traditional Chinese Medicine,Tianjin,China

Further Study Information

Current Stage: Ongoing
Date: January 2020 - June 2021
Funding source(s): None


Health Area

Disease Category: Cancer, Lungs & airways

Disease Name: Lung cancer

Target Population

Age Range: 0 - 120

Sex: Either

Nature of Intervention: Complementary and alternative medicine (CAM) therapy, Traditional Chinese Medicine

Stakeholders Involved

- Clinical experts
- Conference participants
- Consumers (patients)
- Researchers

Study Type

- COS for clinical trials or clinical research
- COS for practice

Method(s)

- Consensus conference
- Delphi process
- Interview
- Systematic review

(1)Systematic literature review
(2) Qualitative semi-structured interview
(3)Two rounds Delphi Survey
(4) Consensus conference

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