Patient-reported outcomes in research on critically ill obstetric patients

Background
Research benefits from the incorporation of patient-important outcomes. We interviewed individuals after a critical illness during pregnancy to identify outcomes for the development of a core outcome set (COS).

Methods
Participants were identified through intensive care unit (ICU) admissions in Toronto, Canada, and Barranquilla, Colombia. Interviewers used a semi-structured guide, and discussions were recorded and transcribed. Transcripts underwent inductive thematic analysis to delineate themes and patient-important outcomes.

Results
Twelve individuals were interviewed. Twenty-six patient-important outcomes were elicited, which represented the core outcome areas of mortality (n?=?1), physiological/clinical outcomes (n?=?7), functioning and life impact (n?=?13), resource use (n?=?4) and adverse events (n?=?1). These related to five identified themes of mental well-being, quality of care delivered, clinicians’ communication, regaining functional independence and mother–newborn separation.

Conclusions
This qualitative study identified patient-important outcomes from persons with lived experience of critical illness in pregnancy which will inform the development of a COS.

Contributors

Julien Viau Lapointe, Clara Juando-Prats, Roberto Zapata, Julia Kfouri, Joyamor Ortuno-Nacho, Rizwana Ashraf, Rohan D’Souza, Jose Rojas-Suarez, Stephen E Lapinsky

Publication

Journal: Obstetric Medicine
Volume:
Issue:
Pages: -
Year: 2024
DOI: https://doi.org/10.1177/1753495X241290681

Further Study Information

Current Stage: Completed
Date:
Funding source(s): The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research is funded by the CHEST Foundation Research Grant in Women's Lung Health. Dr D'Souza is the recipient of a Tier II Canada Research Chair in maternal health [2021–00337].


Health Area

Disease Category: Pregnancy & childbirth

Disease Name: Critical illness , Postpartum Haemorrhage, Severe preeclampsia

Target Population

Age Range: Unknown

Sex: Female

Nature of Intervention: Management of care

Stakeholders Involved

- Consumers (patients)
- Families

Study Type

- Patient perspectives

Method(s)

- Interview